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CRISPR detection of circulating cell-free Mycobacterium tuberculosis DNA in adults and children, including children with HIV: a molecular diagnostics study

BACKGROUND: Tuberculosis remains a leading cause of global mortality, especially for adults and children living with HIV (CLHIV) underdiagnosed by sputum-based assays. Non-sputum-based assays are needed to improve tuberculosis diagnosis and tuberculosis treatment monitoring. Our aim in this study wa...

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Detalles Bibliográficos
Autores principales:	Huang, Zhen, LaCourse, Sylvia M, Kay, Alexander W, Stern, Joshua, Escudero, Jaclyn N, Youngquist, Brady M, Zheng, Wenshu, Vambe, Debrah, Dlamini, Muyalo, Mtetwa, Godwin, Cranmer, Lisa M, Njuguna, Irene, Wamalwa, Dalton C, Maleche-Obimbo, Elizabeth, Catanzaro, Donald G, Lyon, Christopher J, John-Stewart, Grace, DiNardo, Andrew, Mandalakas, Anna M, Ning, Bo, Hu, Tony Y
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9300929/ https://www.ncbi.nlm.nih.gov/pubmed/35659882 http://dx.doi.org/10.1016/S2666-5247(22)00087-8

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