Cargando…
TFP5-Mediated CDK5 Activity Inhibition Improves Diabetic Nephropathy via NGF/Sirt1 Regulating Axis
Diabetic nephropathy (DN) is one of the leading causes of chronic kidney disease (CKD), during which hyperglycemia is composed of the major force for the deterioration to end-stage renal disease (ESRD). However, the underlying mechanism triggering the effect of hyperglycemia on DN is not very clear...
Autores principales: | Cao, Shi-Lu, Luo, Hong-Yan, Gao, Yong-Cai, Lan, Xiao-Mei, Liu, Shun-Yao, Li, Bo, Bao, Li, E., Jing, Ma, Danna, Zhang, Guo-Qing, Yang, Li-Rong, Bao, Xi, Zheng, Ya-Li |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9301001/ https://www.ncbi.nlm.nih.gov/pubmed/35874807 http://dx.doi.org/10.3389/fcell.2022.829067 |
Ejemplares similares
-
SIRT7-Induced PHF5A Decrotonylation Regulates Aging Progress Through Alternative Splicing-Mediated Downregulation of CDK2
por: Yu, Ai Qing, et al.
Publicado: (2021) -
The SIRT1-c-Myc axis in regulation of stem cells
por: Fan, Wei, et al.
Publicado: (2023) -
TFP5 peptide, derived from CDK5-activating cofactor p35, provides neuroprotection in early-stage of adult ischemic stroke
por: Ji, Ya-Bin, et al.
Publicado: (2017) -
Peptide TFP5/TP5 derived from Cdk5 activator P35 provides neuroprotection in the MPTP model of Parkinson’s disease
por: Binukumar, BK., et al.
Publicado: (2015) -
The SIRT1-HMGB1 axis: Therapeutic potential to ameliorate inflammatory responses and tumor occurrence
por: Wei, Lanyi, et al.
Publicado: (2022)