Cargando…
Effects of Small Peptide Supplementation on Growth Performance, Intestinal Barrier of Laying Hens During the Brooding and Growing Periods
The growing period is a critical period for growth and development in laying hens. During this period, chicks grow rapidly, but are accompanied by unstable digestive function, incomplete organ development, and high mortality. Small peptide, a feed additive, which has been proved to promote intestina...
Autores principales: | , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9301363/ https://www.ncbi.nlm.nih.gov/pubmed/35874672 http://dx.doi.org/10.3389/fimmu.2022.925256 |
_version_ | 1784751414850879488 |
---|---|
author | Zhao, Xiyu Zhang, Yao He, Wentao Wei, Yuanhang Han, Shunshun Xia, Lu Tan, Bo Yu, Jie Kang, Houyang Ma, Mengen Zhu, Qing Yin, Huadong Cui, Can |
author_facet | Zhao, Xiyu Zhang, Yao He, Wentao Wei, Yuanhang Han, Shunshun Xia, Lu Tan, Bo Yu, Jie Kang, Houyang Ma, Mengen Zhu, Qing Yin, Huadong Cui, Can |
author_sort | Zhao, Xiyu |
collection | PubMed |
description | The growing period is a critical period for growth and development in laying hens. During this period, chicks grow rapidly, but are accompanied by unstable digestive function, incomplete organ development, and high mortality. Small peptide, a feed additive, which has been proved to promote intestinal development and immunity in poultry. In order to elucidate the effects of small peptides on growth performance, immunity, antioxidant capacity, and intestinal health of growing laying hens, a total of 900 Tianfu green shell laying hens (1-day-old) were randomly divided into 5 treatments with 6 replicates of 30 birds each in this 18-week trial. Dietary treatments included a corn-soybean meal-based diet supplemented with 0 g/kg, 1.5 g/kg, 3.0 g/kg, 4.5 g/kg and 6.0 g/kg small peptide, respectively. The results showed that the supplementation of small peptides significantly increased growth rate (P<0.05) in laying hens, as well as elevated the serum immunoglobulins (P<0.05) and antioxidant indices (P<0.05), however, it decreased inflammation parameters (P<0.05). The supplementation of small peptides enhanced the intestinal function by promoting gut development (P<0.05) and improving gut integrity (P<0.05), barrier function (P<0.05) and the diversity of gut microbiota (P<0.05) in the growing hens. The best performance was recorded among the hens fed 4.5 g/kg level of small peptide. Taken together, these results showed that small peptide supplementation could improve the economic value of growing hens by promoting growth rate, disease resistance, and the optimal amount of addition for Tianfu green shell laying hens was 4.5 g/kg. |
format | Online Article Text |
id | pubmed-9301363 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-93013632022-07-22 Effects of Small Peptide Supplementation on Growth Performance, Intestinal Barrier of Laying Hens During the Brooding and Growing Periods Zhao, Xiyu Zhang, Yao He, Wentao Wei, Yuanhang Han, Shunshun Xia, Lu Tan, Bo Yu, Jie Kang, Houyang Ma, Mengen Zhu, Qing Yin, Huadong Cui, Can Front Immunol Immunology The growing period is a critical period for growth and development in laying hens. During this period, chicks grow rapidly, but are accompanied by unstable digestive function, incomplete organ development, and high mortality. Small peptide, a feed additive, which has been proved to promote intestinal development and immunity in poultry. In order to elucidate the effects of small peptides on growth performance, immunity, antioxidant capacity, and intestinal health of growing laying hens, a total of 900 Tianfu green shell laying hens (1-day-old) were randomly divided into 5 treatments with 6 replicates of 30 birds each in this 18-week trial. Dietary treatments included a corn-soybean meal-based diet supplemented with 0 g/kg, 1.5 g/kg, 3.0 g/kg, 4.5 g/kg and 6.0 g/kg small peptide, respectively. The results showed that the supplementation of small peptides significantly increased growth rate (P<0.05) in laying hens, as well as elevated the serum immunoglobulins (P<0.05) and antioxidant indices (P<0.05), however, it decreased inflammation parameters (P<0.05). The supplementation of small peptides enhanced the intestinal function by promoting gut development (P<0.05) and improving gut integrity (P<0.05), barrier function (P<0.05) and the diversity of gut microbiota (P<0.05) in the growing hens. The best performance was recorded among the hens fed 4.5 g/kg level of small peptide. Taken together, these results showed that small peptide supplementation could improve the economic value of growing hens by promoting growth rate, disease resistance, and the optimal amount of addition for Tianfu green shell laying hens was 4.5 g/kg. Frontiers Media S.A. 2022-07-07 /pmc/articles/PMC9301363/ /pubmed/35874672 http://dx.doi.org/10.3389/fimmu.2022.925256 Text en Copyright © 2022 Zhao, Zhang, He, Wei, Han, Xia, Tan, Yu, Kang, Ma, Zhu, Yin and Cui https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Immunology Zhao, Xiyu Zhang, Yao He, Wentao Wei, Yuanhang Han, Shunshun Xia, Lu Tan, Bo Yu, Jie Kang, Houyang Ma, Mengen Zhu, Qing Yin, Huadong Cui, Can Effects of Small Peptide Supplementation on Growth Performance, Intestinal Barrier of Laying Hens During the Brooding and Growing Periods |
title | Effects of Small Peptide Supplementation on Growth Performance, Intestinal Barrier of Laying Hens During the Brooding and Growing Periods |
title_full | Effects of Small Peptide Supplementation on Growth Performance, Intestinal Barrier of Laying Hens During the Brooding and Growing Periods |
title_fullStr | Effects of Small Peptide Supplementation on Growth Performance, Intestinal Barrier of Laying Hens During the Brooding and Growing Periods |
title_full_unstemmed | Effects of Small Peptide Supplementation on Growth Performance, Intestinal Barrier of Laying Hens During the Brooding and Growing Periods |
title_short | Effects of Small Peptide Supplementation on Growth Performance, Intestinal Barrier of Laying Hens During the Brooding and Growing Periods |
title_sort | effects of small peptide supplementation on growth performance, intestinal barrier of laying hens during the brooding and growing periods |
topic | Immunology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9301363/ https://www.ncbi.nlm.nih.gov/pubmed/35874672 http://dx.doi.org/10.3389/fimmu.2022.925256 |
work_keys_str_mv | AT zhaoxiyu effectsofsmallpeptidesupplementationongrowthperformanceintestinalbarrieroflayinghensduringthebroodingandgrowingperiods AT zhangyao effectsofsmallpeptidesupplementationongrowthperformanceintestinalbarrieroflayinghensduringthebroodingandgrowingperiods AT hewentao effectsofsmallpeptidesupplementationongrowthperformanceintestinalbarrieroflayinghensduringthebroodingandgrowingperiods AT weiyuanhang effectsofsmallpeptidesupplementationongrowthperformanceintestinalbarrieroflayinghensduringthebroodingandgrowingperiods AT hanshunshun effectsofsmallpeptidesupplementationongrowthperformanceintestinalbarrieroflayinghensduringthebroodingandgrowingperiods AT xialu effectsofsmallpeptidesupplementationongrowthperformanceintestinalbarrieroflayinghensduringthebroodingandgrowingperiods AT tanbo effectsofsmallpeptidesupplementationongrowthperformanceintestinalbarrieroflayinghensduringthebroodingandgrowingperiods AT yujie effectsofsmallpeptidesupplementationongrowthperformanceintestinalbarrieroflayinghensduringthebroodingandgrowingperiods AT kanghouyang effectsofsmallpeptidesupplementationongrowthperformanceintestinalbarrieroflayinghensduringthebroodingandgrowingperiods AT mamengen effectsofsmallpeptidesupplementationongrowthperformanceintestinalbarrieroflayinghensduringthebroodingandgrowingperiods AT zhuqing effectsofsmallpeptidesupplementationongrowthperformanceintestinalbarrieroflayinghensduringthebroodingandgrowingperiods AT yinhuadong effectsofsmallpeptidesupplementationongrowthperformanceintestinalbarrieroflayinghensduringthebroodingandgrowingperiods AT cuican effectsofsmallpeptidesupplementationongrowthperformanceintestinalbarrieroflayinghensduringthebroodingandgrowingperiods |