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γ9δ2 T-Cell Expansion and Phenotypic Profile Are Reflected in the CDR3δ Repertoire of Healthy Adults

γ9δ2T cells fill a distinct niche in human immunity due to the unique physiology of the phosphoantigen-reactive γ9δ2TCR. Here, we highlight reproducible TCRδ complementarity-determining region 3 (CDR3δ) repertoire patterns associated with γ9δ2T cell proliferation and phenotype, thus providing eviden...

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Detalles Bibliográficos
Autores principales: Vyborova, Anna, Janssen, Anke, Gatti, Lucrezia, Karaiskaki, Froso, Yonika, Austin, van Dooremalen, Sanne, Sanders, Jasper, Beringer, Dennis X., Straetemans, Trudy, Sebestyen, Zsolt, Kuball, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9301380/
https://www.ncbi.nlm.nih.gov/pubmed/35874769
http://dx.doi.org/10.3389/fimmu.2022.915366