Cargando…
γ9δ2 T-Cell Expansion and Phenotypic Profile Are Reflected in the CDR3δ Repertoire of Healthy Adults
γ9δ2T cells fill a distinct niche in human immunity due to the unique physiology of the phosphoantigen-reactive γ9δ2TCR. Here, we highlight reproducible TCRδ complementarity-determining region 3 (CDR3δ) repertoire patterns associated with γ9δ2T cell proliferation and phenotype, thus providing eviden...
Autores principales: | Vyborova, Anna, Janssen, Anke, Gatti, Lucrezia, Karaiskaki, Froso, Yonika, Austin, van Dooremalen, Sanne, Sanders, Jasper, Beringer, Dennis X., Straetemans, Trudy, Sebestyen, Zsolt, Kuball, Jürgen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9301380/ https://www.ncbi.nlm.nih.gov/pubmed/35874769 http://dx.doi.org/10.3389/fimmu.2022.915366 |
Ejemplares similares
-
Gamma delta TCR anti-CD3 bispecific molecules (GABs) as novel immunotherapeutic compounds
por: van Diest, Eline, et al.
Publicado: (2021) -
The Role of γδ T Cells as a Line of Defense in Viral Infections after Allogeneic Stem Cell Transplantation: Opportunities and Challenges
por: Janssen, Anke, et al.
Publicado: (2022) -
Cellular immunotherapy on primary multiple myeloma expanded in a 3D bone marrow niche model
por: Braham, Maaike V. J., et al.
Publicado: (2018) -
Characterization and modulation of anti-αβTCR antibodies and their respective binding sites at the βTCR chain to enrich engineered T cells
por: Kierkels, Guido J.J., et al.
Publicado: (2021) -
Adding Help to an HLA-A*24:02 Tumor-Reactive γδTCR Increases Tumor Control
por: Johanna, Inez, et al.
Publicado: (2021)