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Microcystin-LR incorporated into colonic cells through probenecid-sensitive transporters leads to upregulated MCP-1 expression induced by JNK activation

Harmful algae that inhabit eutrophic lakes produce cyanotoxic microcystins. Therefore, the relationship between chronic exposure to microcystins via drinking water and organ disorders has been investigated. The present study aimed to determine whether representative microcystin-LR is involved in inc...

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Detalles Bibliográficos
Autores principales: Koto, Yoshihito, Kawahara, Hideaki, Kurata, Koichi, Yoshikiyo, Keisuke, Hashiguchi, Ayumi, Okano, Kunihiro, Sugiura, Norio, Shimizu, Kazuya, Shimizu, Hidehisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9301606/
https://www.ncbi.nlm.nih.gov/pubmed/35875256
http://dx.doi.org/10.1016/j.toxrep.2022.04.019