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Tricyclic Aza-Andrographolide Derivatives from Late-Stage Hydroamination and Their Anti-human Coronavirus (Anti-HCoV) Activity

[Image: see text] A late-stage functionalization (LSF) of the natural product andrographolide for the efficient assembly of a range of structurally interesting and diverse tricyclic-aza derivatives was developed. The key to the diversification is a photo-catalyzed intramolecular hydroamination react...

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Detalles Bibliográficos
Autores principales: Che, Chao, Jiang, Ding, Zhang, Jiayin, Xing, Qi, Li, Ting, Zhao, Yi, Guan, Liangyu, Chen, Huangcan, Xiang, Dehu, Di, Man, Zhu, Zhendong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9301648/
https://www.ncbi.nlm.nih.gov/pubmed/35874238
http://dx.doi.org/10.1021/acsomega.2c02979