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Using NMR to Dissect the Chemical Space and O-Sulfation Effects within the O- and S-Glycoside Analogues of Heparan Sulfate

[Image: see text] Heparan sulfate (HS), a sulfated linear carbohydrate that decorates the cell surface and extracellular matrix, is ubiquitously distributed throughout the animal kingdom and represents a key regulator of biological processes and a largely untapped reservoir of potential therapeutic...

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Detalles Bibliográficos
Autores principales: Meneghetti, Maria C.Z., Naughton, Lucy, O’Shea, Conor, Koffi Teki, Dindet S.-E., Chagnault, Vincent, Nader, Helena B., Rudd, Timothy R., Yates, Edwin A., Kovensky, José, Miller, Gavin J., Lima, Marcelo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9301708/
https://www.ncbi.nlm.nih.gov/pubmed/35874203
http://dx.doi.org/10.1021/acsomega.2c02070