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Non-Native Amino Acid Click Chemistry-Based Technology for Site-Specific Polysaccharide Conjugation to a Bacterial Protein Serving as Both Carrier and Vaccine Antigen
[Image: see text] Surface-expressed bacterial polysaccharides are important vaccine antigens but must be conjugated to a carrier protein for efficient antigen presentation and development of strong memory B cell and antibody responses, especially in young children. The commonly used protein carriers...
Autores principales: | Kapoor, Neeraj, Uchiyama, Satoshi, Pill, Lucy, Bautista, Leslie, Sedra, Angie, Yin, Lu, Regan, Maritoni, Chu, Ellen, Rabara, Taylor, Wong, Melissa, Davey, Peter, Fairman, Jeff, Nizet, Victor |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9301713/ https://www.ncbi.nlm.nih.gov/pubmed/35874267 http://dx.doi.org/10.1021/acsomega.1c07360 |
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