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Intent-to-Treat (ITT) vs Completer or Per-Protocol Analysis in Randomized Controlled Trials
In randomized controlled trials, randomization creates groups that are reasonably well balanced on all baseline variables, whether measured, unmeasured, or unknown. Postbaseline events disturb this balance, resulting in postrandomization biases. Drop-out is one such event. There are two main methods...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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SAGE Publications
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9301744/ https://www.ncbi.nlm.nih.gov/pubmed/35949630 http://dx.doi.org/10.1177/02537176221101996 |