Ablation of Siglec-E augments brain inflammation and ischemic injury

Sialic acid immunoglobulin-like lectin E (Siglec-E) is a subtype of pattern recognition receptors found on the surface of myeloid cells and functions as a key immunosuppressive checkpoint molecule. The engagement between Siglec-E and the ligand α(2,8)-linked disialyl glycans activates the immunorece...

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Detalles Bibliográficos
Autores principales: Li, Lexiao, Chen, Yu, Sluter, Madison N., Hou, Ruida, Hao, Jiukuan, Wu, Yin, Chen, Guo-Yun, Yu, Ying, Jiang, Jianxiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9301848/
https://www.ncbi.nlm.nih.gov/pubmed/35858866
http://dx.doi.org/10.1186/s12974-022-02556-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9301848/
https://www.ncbi.nlm.nih.gov/pubmed/35858866
http://dx.doi.org/10.1186/s12974-022-02556-1

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