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Ablation of Siglec-E augments brain inflammation and ischemic injury
Sialic acid immunoglobulin-like lectin E (Siglec-E) is a subtype of pattern recognition receptors found on the surface of myeloid cells and functions as a key immunosuppressive checkpoint molecule. The engagement between Siglec-E and the ligand α(2,8)-linked disialyl glycans activates the immunorece...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9301848/ https://www.ncbi.nlm.nih.gov/pubmed/35858866 http://dx.doi.org/10.1186/s12974-022-02556-1 |