Mechanistic elucidation of freezing-induced surface decomposition of aluminum oxyhydroxide adjuvant

The freezing-induced aggregation of aluminum-based (Alum) adjuvants has been considered as the most important cause of reduced vaccine potency. However, the intrinsic properties that determine the functionality of Alum after freezing have not been elucidated. In this study, we used engineered alumin...

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Detalles Bibliográficos
Autores principales: Li, Jiahuan, Yu, Ge, Liang, Zhihui, Li, Min, Chen, Chen, Li, Xin, Guo, Yiyang, Yang, Cheng, Liu, Yang, Zhang, Caiqiao, Zhang, Weiting, Liu, Jiaxu, Ma, Xuehu, Xue, Changying, Sun, Bingbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9301878/
https://www.ncbi.nlm.nih.gov/pubmed/35874920
http://dx.doi.org/10.1016/j.isci.2022.104456

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