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Immunomodulation and endothelial barrier protection mediate the association between oral imatinib and mortality in hospitalised COVID-19 patients

BACKGROUND: Imatinib reduced 90-day mortality in hospitalised coronavirus disease 2019 (COVID-19) patients in a recent clinical trial, but the biological effects that cause improved clinical outcomes are unknown. We aimed to determine the biological changes elicited by imatinib in patients with COVI...

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Detalles Bibliográficos
Autores principales:	de Brabander, Justin, Duijvelaar, Erik, Schippers, Job R., Smeele, Patrick J., Peters-Sengers, Hessel, Duitman, Jan Willem, Aman, Jurjan, Bogaard, Harm Jan, van der Poll, Tom, Bos, Lieuwe D.J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	European Respiratory Society 2022
Materias:	Original Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9301934/ https://www.ncbi.nlm.nih.gov/pubmed/35896211 http://dx.doi.org/10.1183/13993003.00780-2022

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