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Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)-s-triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades

[Image: see text] Here, we synthesized a newseries of mono- and bis(dimethylpyrazolyl)-s-triazine derivatives. The synthetic methodology involved the reaction of different mono- and dihydrazinyl-s-triazine derivatives with acetylacetone in the presence of triethylamine to produce the corresponding t...

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Detalles Bibliográficos
Autores principales:	Shawish, Ihab, Barakat, Assem, Aldalbahi, Ali, Malebari, Azizah M., Nafie, Mohamed S., Bekhit, Adnan A., Albohy, Amgad, Khan, Alamgir, Ul-Haq, Zaheer, Haukka, Matti, de la Torre, Beatriz G., Albericio, Fernando, El-Faham, Ayman
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9301957/ https://www.ncbi.nlm.nih.gov/pubmed/35874229 http://dx.doi.org/10.1021/acsomega.2c03079

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