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Autism-associated chromatin remodeler CHD8 regulates erythroblast cytokinesis and fine-tunes the balance of Rho GTPase signaling

CHD8 is an ATP-dependent chromatin-remodeling factor whose monoallelic mutation defines a subtype of autism spectrum disorders (ASDs). Previous work found that CHD8 is required for the maintenance of hematopoiesis by integrating ATM-P53-mediated survival of hematopoietic stem/progenitor cells (HSPCs...

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Detalles Bibliográficos
Autores principales:	Tu, Zhaowei, Fan, Cuiqing, Davis, Ashely K., Hu, Mengwen, Wang, Chen, Dandamudi, Akhila, Seu, Katie G., Kalfa, Theodosia A., Lu, Q. Richard, Zheng, Yi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9302451/ https://www.ncbi.nlm.nih.gov/pubmed/35830790 http://dx.doi.org/10.1016/j.celrep.2022.111072

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