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Solamargine inhibits the growth of hepatocellular carcinoma and enhances the anticancer effect of sorafenib by regulating HOTTIP‐TUG1/miR‐4726‐5p/MUC1 pathway
Hepatocellular carcinoma (HCC) is one of the most common primary malignancies. Drug resistance has significantly prevented the clinical application of sorafenib (SF), a first‐line targeted medicine for the treatment of HCC. Solamargine (SM), a natural alkaloid, has shown potential antitumor activity...
Autores principales: | Tang, Qing, Li, Xiaojuan, Chen, Yun, Long, Shunqin, Yu, Yaya, Sheng, Honghao, Wang, Sumei, Han, Ling, Wu, Wanyin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9302658/ https://www.ncbi.nlm.nih.gov/pubmed/35040191 http://dx.doi.org/10.1002/mc.23389 |
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