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Structure-selected RBM immunogens prime polyclonal memory responses that neutralize SARS-CoV-2 variants of concern

Successful control of the COVID-19 pandemic depends on vaccines that prevent transmission. The full-length Spike protein is highly immunogenic but the majority of antibodies do not target the virus: ACE2 interface. In an effort to affect the quality of the antibody response focusing it to the recept...

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Detalles Bibliográficos
Autores principales:	Almanza, Gonzalo, Clark, Alex E., Kouznetsova, Valentina, Olmedillas, Eduardo, Castro, Andrea, Tsigelny, Igor F., Wu, Yan, Gao, George F., Leibel, Sandra L., Bray, William, Ollmann Saphire, Erica, Carlin, Aaron F., Zanetti, Maurizio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9302722/ https://www.ncbi.nlm.nih.gov/pubmed/35862442 http://dx.doi.org/10.1371/journal.ppat.1010686

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