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Epigenetic and transcriptome responsiveness to ER modulation by tissue selective estrogen complexes in breast epithelial and breast cancer cells

Selective estrogen receptor modulators (SERMs), including the SERM/SERD bazedoxifene (BZA), are used to treat postmenopausal osteoporosis and may reduce breast cancer (BCa) risk. One of the most persistent unresolved questions regarding menopausal hormone therapy is compromised control of proliferat...

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Detalles Bibliográficos
Autores principales: Messier, Terri L., Boyd, Joseph R., Gordon, Jonathan A. R., Tye, Coralee E., Page, Natalie A., Toor, Rabail H., Zaidi, Sayyed K., Komm, Barry S., Frietze, Seth, Stein, Janet L., Lian, Jane B., Stein, Gary S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9302754/
https://www.ncbi.nlm.nih.gov/pubmed/35862394
http://dx.doi.org/10.1371/journal.pone.0271725