Widespread emergence of OmpK36 loop 3 insertions among multidrug-resistant clones of Klebsiella pneumoniae

Mutations in outer membrane porins act in synergy with carbapenemase enzymes to increase carbapenem resistance in the important nosocomial pathogen, Klebsiella pneumoniae (KP). A key example is a di-amino acid insertion, Glycine-Aspartate (GD), in the extracellular loop 3 (L3) region of OmpK36 which...

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Detalles Bibliográficos
Autores principales: David, Sophia, Wong, Joshua L. C., Sanchez-Garrido, Julia, Kwong, Hok-Sau, Low, Wen Wen, Morecchiato, Fabio, Giani, Tommaso, Rossolini, Gian Maria, Brett, Stephen J., Clements, Abigail, Beis, Konstantinos, Aanensen, David M., Frankel, Gad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9302836/
https://www.ncbi.nlm.nih.gov/pubmed/35816554
http://dx.doi.org/10.1371/journal.ppat.1010334

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9302836/
https://www.ncbi.nlm.nih.gov/pubmed/35816554
http://dx.doi.org/10.1371/journal.ppat.1010334

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