Three enigmatic BioH isoenzymes are programmed in the early stage of mycobacterial biotin synthesis, an attractive anti-TB drug target

Tuberculosis (TB) is one of the leading infectious diseases of global concern, and one quarter of the world’s population are TB carriers. Biotin metabolism appears to be an attractive anti-TB drug target. However, the first-stage of mycobacterial biotin synthesis is fragmentarily understood. Here we...

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Detalles Bibliográficos
Autores principales: Xu, Yongchang, Yang, Jie, Li, Weihui, Song, Shuaijie, Shi, Yu, Wu, Lihan, Sun, Jingdu, Hou, Mengyun, Wang, Jinzi, Jia, Xu, Zhang, Huimin, Huang, Man, Lu, Ting, Gan, Jianhua, Feng, Youjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9302846/
https://www.ncbi.nlm.nih.gov/pubmed/35816546
http://dx.doi.org/10.1371/journal.ppat.1010615

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