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Nicotine promotes vascular calcification via intracellular Ca(2+)-mediated, Nox5-induced oxidative stress, and extracellular vesicle release in vascular smooth muscle cells

AIMS: Smokers are at increased risk of cardiovascular events. However, the exact mechanisms through which smoking influences cardiovascular disease resulting in accelerated atherosclerosis and vascular calcification are unknown. The aim of this study was to investigate effects of nicotine on initiat...

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Detalles Bibliográficos
Autores principales:	Petsophonsakul, Ploingarm, Burgmaier, Mathias, Willems, Brecht, Heeneman, Sylvia, Stadler, Nadina, Gremse, Felix, Reith, Sebastian, Burgmaier, Kathrin, Kahles, Florian, Marx, Nikolaus, Natour, Ehsan, Bidar, Elham, Jacobs, Michael, Mees, Barend, Reutelingsperger, Chris, Furmanik, Malgorzata, Schurgers, Leon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9302892/ https://www.ncbi.nlm.nih.gov/pubmed/34273166 http://dx.doi.org/10.1093/cvr/cvab244

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