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Citrate Synthase Insufficiency Leads to Specific Metabolic Adaptations in the Heart and Skeletal Muscles Upon Low-Carbohydrate Diet Feeding in Mice
A decrease in TCA cycle activity may lead to impaired nutrition metabolism and cellular energy shortage. Herein, we aimed to characterize the detailed metabolic changes that compensate for energy shortages in energy-consuming organs (heart and skeletal muscles) in mice with knockout of citrate synth...
Autores principales: | Sumi, Kanako, Hatanaka, Yuiko, Takahashi, Reina, Wada, Naoko, Ono, Chihiro, Sakamoto, Yuri, Sone, Hirohito, Iida, Kaoruko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9302927/ https://www.ncbi.nlm.nih.gov/pubmed/35873436 http://dx.doi.org/10.3389/fnut.2022.925908 |
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