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Recent progress in natural dietary non-phenolic bioactives on cancers metastasis
From several decades ago to now, cancer continues to be the leading cause of death worldwide, and metastasis is the major cause of cancer-related deaths. For health benefits, there is a great desire to use non-chemical therapy such as nutraceutical supplementation to prevent pathology development. O...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taiwan Food and Drug Administration
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303016/ https://www.ncbi.nlm.nih.gov/pubmed/29976413 http://dx.doi.org/10.1016/j.jfda.2018.05.003 |
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author | Yen, Gow-Chin Tsai, Chiung-Man Lu, Chi-Cheng Weng, Chia-Jui |
author_facet | Yen, Gow-Chin Tsai, Chiung-Man Lu, Chi-Cheng Weng, Chia-Jui |
author_sort | Yen, Gow-Chin |
collection | PubMed |
description | From several decades ago to now, cancer continues to be the leading cause of death worldwide, and metastasis is the major cause of cancer-related deaths. For health benefits, there is a great desire to use non-chemical therapy such as nutraceutical supplementation to prevent pathology development. Over 10,000 different natural bioactives or phytochemicals have been known that possessing potential preventive or supplementary effects for various diseases including cancer. Previously, the in vitro and in vivo anti-invasive and anti-metastatic activities of phenolic acids, monophenol, polyphenol and their derivatives and flavonoids and their derivatives have been reviewed. However, a vast number of natural dietary compounds other than phenolics have been demonstrated to potentially possess the ability to inhibit the invasion and metastasis of various cancers. In this review, we summarize the studies in recent decade on in vitro and in vivo effects and molecular mechanisms of natural bioactives, excluding the phenolics in food, in cancer invasion and metastasis. By combining this review of non-phenolics with the previous phenolics reviews, the puzzle for the contribution of natural dietary bioactives on cancer invasive or/and metastatic progress will be almost complete and more clear. |
format | Online Article Text |
id | pubmed-9303016 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Taiwan Food and Drug Administration |
record_format | MEDLINE/PubMed |
spelling | pubmed-93030162022-08-09 Recent progress in natural dietary non-phenolic bioactives on cancers metastasis Yen, Gow-Chin Tsai, Chiung-Man Lu, Chi-Cheng Weng, Chia-Jui J Food Drug Anal Review Article From several decades ago to now, cancer continues to be the leading cause of death worldwide, and metastasis is the major cause of cancer-related deaths. For health benefits, there is a great desire to use non-chemical therapy such as nutraceutical supplementation to prevent pathology development. Over 10,000 different natural bioactives or phytochemicals have been known that possessing potential preventive or supplementary effects for various diseases including cancer. Previously, the in vitro and in vivo anti-invasive and anti-metastatic activities of phenolic acids, monophenol, polyphenol and their derivatives and flavonoids and their derivatives have been reviewed. However, a vast number of natural dietary compounds other than phenolics have been demonstrated to potentially possess the ability to inhibit the invasion and metastasis of various cancers. In this review, we summarize the studies in recent decade on in vitro and in vivo effects and molecular mechanisms of natural bioactives, excluding the phenolics in food, in cancer invasion and metastasis. By combining this review of non-phenolics with the previous phenolics reviews, the puzzle for the contribution of natural dietary bioactives on cancer invasive or/and metastatic progress will be almost complete and more clear. Taiwan Food and Drug Administration 2018-06-01 /pmc/articles/PMC9303016/ /pubmed/29976413 http://dx.doi.org/10.1016/j.jfda.2018.05.003 Text en © 2018 Taiwan Food and Drug Administration https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC-BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) ). |
spellingShingle | Review Article Yen, Gow-Chin Tsai, Chiung-Man Lu, Chi-Cheng Weng, Chia-Jui Recent progress in natural dietary non-phenolic bioactives on cancers metastasis |
title | Recent progress in natural dietary non-phenolic bioactives on cancers metastasis |
title_full | Recent progress in natural dietary non-phenolic bioactives on cancers metastasis |
title_fullStr | Recent progress in natural dietary non-phenolic bioactives on cancers metastasis |
title_full_unstemmed | Recent progress in natural dietary non-phenolic bioactives on cancers metastasis |
title_short | Recent progress in natural dietary non-phenolic bioactives on cancers metastasis |
title_sort | recent progress in natural dietary non-phenolic bioactives on cancers metastasis |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303016/ https://www.ncbi.nlm.nih.gov/pubmed/29976413 http://dx.doi.org/10.1016/j.jfda.2018.05.003 |
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