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Recurrence of signs consistent with cervical intervertebral disc extrusion in dogs

OBJECTIVES: Report the rate of recurrent clinical signs following successful treatment of cervical intervertebral disc extrusion, and explore the association between treatment method and recurrence. MATERIALS AND METHODS: Medical records of dogs with MRI‐ or CT‐confirmed cervical intervertebral disc...

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Autores principales: Argent, V., Perillo, R., Jeffery, N., Freeman, P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303190/
https://www.ncbi.nlm.nih.gov/pubmed/35146745
http://dx.doi.org/10.1111/jsap.13480
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author Argent, V.
Perillo, R.
Jeffery, N.
Freeman, P.
author_facet Argent, V.
Perillo, R.
Jeffery, N.
Freeman, P.
author_sort Argent, V.
collection PubMed
description OBJECTIVES: Report the rate of recurrent clinical signs following successful treatment of cervical intervertebral disc extrusion, and explore the association between treatment method and recurrence. MATERIALS AND METHODS: Medical records of dogs with MRI‐ or CT‐confirmed cervical intervertebral disc extrusion were reviewed to verify that they recovered. Type of treatment, site of initial extrusion and whether dogs re‐presented with recurrent clinical signs were recorded. Recurrence was considered presumed if based on clinical signs or confirmed if based on repeat cross‐sectional imaging. RESULTS: Complete recovery was documented following medical (36/119, 30.3%) or surgical (83/119, 69.7%) management of initial cervical disc extrusion. There was a recurrence of consistent clinical signs in 40 of 119 (34%) cases, of which 27 of 83 (33%) were initially managed surgically and 13 of 36 (36%) medically. In 24 of 40 (60%) cases, there was imaging confirmation of recurrent extrusion; in medically managed dogs, recurrence mostly occurred at the same site, whereas after surgery, recurrence most commonly involved an adjacent disc. Of the 40 recurrences, 32 (80%) occurred within 2 years of diagnosis. Rate of recurrence was similar between treatment methods in both univariable and multivariable time‐to‐event analyses (hazard ratio 1.03; 95% confidence interval: 0.67 to 1.53; P=0.87). CLINICAL SIGNIFICANCE: Following successful initial medical or surgical treatment, clinical signs consistent with recurrent cervical disc extrusion occurred with similar frequency. Medically treated cases tended to have recurrence at the same site as initial presentation, whereas surgical treatment prevented this. Recurrence usually occurred within 2 years. The retrospective study design, small number of recurrences and lack of imaging confirmation of every recurrence should be considered when interpreting the results.
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spelling pubmed-93031902022-07-22 Recurrence of signs consistent with cervical intervertebral disc extrusion in dogs Argent, V. Perillo, R. Jeffery, N. Freeman, P. J Small Anim Pract Original Articles OBJECTIVES: Report the rate of recurrent clinical signs following successful treatment of cervical intervertebral disc extrusion, and explore the association between treatment method and recurrence. MATERIALS AND METHODS: Medical records of dogs with MRI‐ or CT‐confirmed cervical intervertebral disc extrusion were reviewed to verify that they recovered. Type of treatment, site of initial extrusion and whether dogs re‐presented with recurrent clinical signs were recorded. Recurrence was considered presumed if based on clinical signs or confirmed if based on repeat cross‐sectional imaging. RESULTS: Complete recovery was documented following medical (36/119, 30.3%) or surgical (83/119, 69.7%) management of initial cervical disc extrusion. There was a recurrence of consistent clinical signs in 40 of 119 (34%) cases, of which 27 of 83 (33%) were initially managed surgically and 13 of 36 (36%) medically. In 24 of 40 (60%) cases, there was imaging confirmation of recurrent extrusion; in medically managed dogs, recurrence mostly occurred at the same site, whereas after surgery, recurrence most commonly involved an adjacent disc. Of the 40 recurrences, 32 (80%) occurred within 2 years of diagnosis. Rate of recurrence was similar between treatment methods in both univariable and multivariable time‐to‐event analyses (hazard ratio 1.03; 95% confidence interval: 0.67 to 1.53; P=0.87). CLINICAL SIGNIFICANCE: Following successful initial medical or surgical treatment, clinical signs consistent with recurrent cervical disc extrusion occurred with similar frequency. Medically treated cases tended to have recurrence at the same site as initial presentation, whereas surgical treatment prevented this. Recurrence usually occurred within 2 years. The retrospective study design, small number of recurrences and lack of imaging confirmation of every recurrence should be considered when interpreting the results. Blackwell Publishing Ltd 2022-02-10 2022-06 /pmc/articles/PMC9303190/ /pubmed/35146745 http://dx.doi.org/10.1111/jsap.13480 Text en © 2022 The Authors. Journal of Small Animal Practice published by John Wiley & Sons Ltd on behalf of British Small Animal Veterinary Association https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Original Articles
Argent, V.
Perillo, R.
Jeffery, N.
Freeman, P.
Recurrence of signs consistent with cervical intervertebral disc extrusion in dogs
title Recurrence of signs consistent with cervical intervertebral disc extrusion in dogs
title_full Recurrence of signs consistent with cervical intervertebral disc extrusion in dogs
title_fullStr Recurrence of signs consistent with cervical intervertebral disc extrusion in dogs
title_full_unstemmed Recurrence of signs consistent with cervical intervertebral disc extrusion in dogs
title_short Recurrence of signs consistent with cervical intervertebral disc extrusion in dogs
title_sort recurrence of signs consistent with cervical intervertebral disc extrusion in dogs
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303190/
https://www.ncbi.nlm.nih.gov/pubmed/35146745
http://dx.doi.org/10.1111/jsap.13480
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