SETDB1 acts as a topological accessory to Cohesin via an H3K9me3-independent, genomic shunt for regulating cell fates

SETDB1 is a key regulator of lineage-specific genes and endogenous retroviral elements (ERVs) through its deposition of repressive H3K9me3 mark. Apart from its H3K9me3 regulatory role, SETDB1 has seldom been studied in terms of its other potential regulatory roles. To investigate this, a genomic sur...

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Detalles Bibliográficos
Autores principales: Warrier, Tushar, El Farran, Chadi, Zeng, Yingying, Ho, Benedict Shao Quan, Bao, Qiuye, Zheng, Zi Hao, Bi, Xuezhi, Ng, Huck Hui, Ong, Derrick Sek Tong, Chu, Justin Jang Hann, Sanyal, Amartya, Fullwood, Melissa Jane, Collins, James J, Li, Hu, Xu, Jian, Loh, Yuin-Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303280/
https://www.ncbi.nlm.nih.gov/pubmed/35776115
http://dx.doi.org/10.1093/nar/gkac531

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