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Regulated dicing of pre-mir-144 via reshaping of its terminal loop

Although the route to generate microRNAs (miRNAs) is often depicted as a linear series of sequential and constitutive cleavages, we now appreciate multiple alternative pathways as well as diverse strategies to modulate their processing and function. Here, we identify an unusually profound regulatory...

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Detalles Bibliográficos
Autores principales: Shang, Renfu, Kretov, Dmitry A, Adamson, Scott I, Treiber, Thomas, Treiber, Nora, Vedanayagam, Jeffrey, Chuang, Jeffrey H, Meister, Gunter, Cifuentes, Daniel, Lai, Eric C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303283/
https://www.ncbi.nlm.nih.gov/pubmed/35801921
http://dx.doi.org/10.1093/nar/gkac568