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Quantitative contribution of the spacer length in the supercoiling-sensitivity of bacterial promoters

DNA supercoiling acts as a global transcriptional regulator in bacteria, but the promoter sequence or structural determinants controlling its effect remain unclear. It was previously proposed to modulate the torsional angle between the −10 and −35 hexamers, and thereby regulate the formation of the...

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Detalles Bibliográficos
Autores principales: Forquet, Raphaël, Nasser, William, Reverchon, Sylvie, Meyer, Sam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303308/
https://www.ncbi.nlm.nih.gov/pubmed/35776118
http://dx.doi.org/10.1093/nar/gkac579

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