Conjugation of chemical handles and functional moieties to DNA during solid phase synthesis with sulfonyl azides

Labelling of oligonucleotides with dyes, targeting ligands, and other moieties has become ever more essential in life-sciences. Conventionally, modifications are introduced to oligonucleotides during solid phase synthesis by special phosphoramidites functionalised with a chemical handle or the desir...

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Detalles Bibliográficos
Autores principales: Santorelli, Angel, Gothelf, Kurt V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Chemical Biology and Nucleic Acid Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303310/
https://www.ncbi.nlm.nih.gov/pubmed/35801866
http://dx.doi.org/10.1093/nar/gkac566

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303310/
https://www.ncbi.nlm.nih.gov/pubmed/35801866
http://dx.doi.org/10.1093/nar/gkac566

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