Cargando…
Conjugation of chemical handles and functional moieties to DNA during solid phase synthesis with sulfonyl azides
Labelling of oligonucleotides with dyes, targeting ligands, and other moieties has become ever more essential in life-sciences. Conventionally, modifications are introduced to oligonucleotides during solid phase synthesis by special phosphoramidites functionalised with a chemical handle or the desir...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303310/ https://www.ncbi.nlm.nih.gov/pubmed/35801866 http://dx.doi.org/10.1093/nar/gkac566 |