N‐Acylethanolamine acid amidase (NAAA) is dysregulated in colorectal cancer patients and its inhibition reduces experimental cancer growth

BACKGROUND AND PURPOSE: N‐Acylethanolamine acid amidase (NAAA) is a lysosomal enzyme accountable for the breakdown of N‐acylethanolamines (NAEs) and its pharmacological inhibition has beneficial effects in inflammatory conditions. The knowledge of NAAA in cancer is fragmentary with an unclarified me...

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Detalles Bibliográficos
Autores principales: Romano, Barbara, Pagano, Ester, Iannotti, Fabio A., Piscitelli, Fabiana, Brancaleone, Vincenzo, Lucariello, Giuseppe, Nanì, Maria Francesca, Fiorino, Ferdinando, Sparaco, Rosa, Vanacore, Giovanna, Di Tella, Federica, Cicia, Donatella, Lionetti, Ruggero, Makriyannis, Alexandros, Malamas, Michael, De Luca, Marcello, Aprea, Giovanni, D'Armiento, Maria, Capasso, Raffaele, Sbarro, Bernardo, Venneri, Tommaso, Di Marzo, Vincenzo, Borrelli, Francesca, Izzo, Angelo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303321/
https://www.ncbi.nlm.nih.gov/pubmed/34791641
http://dx.doi.org/10.1111/bph.15737

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