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Neuromelanin‐MRI to Quantify and Track Nigral Depigmentation in Parkinson's Disease: A Multicenter Longitudinal Study Using Template‐Based Standardized Analysis
BACKGROUND: Clinical diagnosis and monitoring of Parkinson's disease (PD) remain challenging because of the lack of an established biomarker. Neuromelanin‐magnetic resonance imaging (NM‐MRI) is an emerging biomarker of nigral depigmentation indexing the loss of melanized neurons but has unknown...
Autores principales: | Xing, Yue, Sapuan, Abdul Halim, Martín‐Bastida, Antonio, Naidu, Saadnah, Tench, Christopher, Evans, Jonathan, Sare, Gillian, Schwarz, Stefan T., Al‐bachari, Sarah, Parkes, Laura M., Kanavou, Sofia, Raw, Jason, Silverdale, Monty, Bajaj, Nin, Pavese, Nicola, Burn, David, Piccini, Paola, Grosset, Donald G., Auer, Dorothee P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303322/ https://www.ncbi.nlm.nih.gov/pubmed/35165920 http://dx.doi.org/10.1002/mds.28934 |
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