Pharmacokinetic and pharmacodynamic equivalence of Biocon's biosimilar Insulin‐R with the US‐licensed Humulin® R formulation in healthy subjects: Results from the RHINE‐1 (Recombinant Human INsulin Equivalence‐1) study

AIM: To establish equivalence in the pharmacokinetic (PK) and pharmacodynamic (PD) endpoints between proposed biosimilar Insulin‐R (Biocon's Insulin‐R) and Humulin® R using the euglycaemic clamp technique in healthy subjects. MATERIALS AND METHODS: In this phase‐1 automated euglycaemic glucose...

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Detalles Bibliográficos
Autores principales: Plum‐Mörschel, Leona, Singh, Gursharan, Murugesan, Sundara Moorthi Nainar, Marwah, Ashwani, Panda, Jayanti, Loganathan, Subramanian, Athalye, Sandeep N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303355/
https://www.ncbi.nlm.nih.gov/pubmed/34981621
http://dx.doi.org/10.1111/dom.14635

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303355/
https://www.ncbi.nlm.nih.gov/pubmed/34981621
http://dx.doi.org/10.1111/dom.14635

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