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Altered medial prefrontal cortex and dorsal raphé activity predict genotype and correlate with abnormal learning behavior in a mouse model of autism‐associated 2p16.3 deletion

2p16.3 deletion, involving NEUREXIN1 (NRXN1) heterozygous deletion, substantially increases the risk of developing autism and other neurodevelopmental disorders. We have a poor understanding of how NRXN1 heterozygosity impacts on brain function and cognition to increase the risk of developing the di...

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Detalles Bibliográficos
Autores principales: Hughes, Rebecca B., Whittingham‐Dowd, Jayde, Clapcote, Steven J., Broughton, Susan J., Dawson, Neil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303357/
https://www.ncbi.nlm.nih.gov/pubmed/35142069
http://dx.doi.org/10.1002/aur.2685

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