Cargando…

Delivery of antisense oligonucleotides for splice‐correction of androgen receptor pre‐mRNA in castration‐resistant prostate cancer models using cell‐penetrating peptides

BACKGROUND: Cell‐penetrating peptides (CPPs) are a promising approach for delivering antisense oligonucleotides (AONs) as they form nanosized complexes through noncovalent interactions that show efficient cellular uptake. Previously, we have designed an AON system to correct splicing of the androgen...

Descripción completa

Detalles Bibliográficos
Autores principales: Luna Velez, Maria V., Paulino da Silva Filho, Omar, Verhaegh, Gerald W., van Hooij, Onno, El Boujnouni, Najoua, Brock, Roland, Schalken, Jack A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303360/
https://www.ncbi.nlm.nih.gov/pubmed/35098567
http://dx.doi.org/10.1002/pros.24309