Synthesis of Aminoethyl‐Substituted Piperidine Derivatives as σ(1) Receptor Ligands with Antiproliferative Properties

A series of novel σ(1) receptor ligands with a 4‐(2‐aminoethyl)piperidine scaffold was prepared and biologically evaluated. The underlying concept of our project was the improvement of the lipophilic ligand efficiency of previously synthesized potent σ(1) ligands. The key steps of the synthesis comp...

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Detalles Bibliográficos
Autores principales: Holtschulte, Catharina, Börgel, Frederik, Westphälinger, Stefanie, Schepmann, Dirk, Civenni, Gianluca, Laurini, Erik, Marson, Domenico, Catapano, Carlo V., Pricl, Sabrina, Wünsch, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303367/
https://www.ncbi.nlm.nih.gov/pubmed/35077612
http://dx.doi.org/10.1002/cmdc.202100735

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303367/
https://www.ncbi.nlm.nih.gov/pubmed/35077612
http://dx.doi.org/10.1002/cmdc.202100735

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