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Synthesis of Aminoethyl‐Substituted Piperidine Derivatives as σ(1) Receptor Ligands with Antiproliferative Properties
A series of novel σ(1) receptor ligands with a 4‐(2‐aminoethyl)piperidine scaffold was prepared and biologically evaluated. The underlying concept of our project was the improvement of the lipophilic ligand efficiency of previously synthesized potent σ(1) ligands. The key steps of the synthesis comp...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303367/ https://www.ncbi.nlm.nih.gov/pubmed/35077612 http://dx.doi.org/10.1002/cmdc.202100735 |