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Dual role of histone variant H3.3B in spermatogenesis: positive regulation of piRNA transcription and implication in X-chromosome inactivation

The histone variant H3.3 is encoded by two distinct genes, H3f3a and H3f3b, exhibiting identical amino-acid sequence. H3.3 is required for spermatogenesis, but the molecular mechanism of its spermatogenic function remains obscure. Here, we have studied the role of each one of H3.3A and H3.3B protein...

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Detalles Bibliográficos
Autores principales: Fontaine, Emeline, Papin, Christophe, Martinez, Guillaume, Le Gras, Stéphanie, Nahed, Roland Abi, Héry, Patrick, Buchou, Thierry, Ouararhni, Khalid, Favier, Bertrand, Gautier, Thierry, Sabir, Jamal S M, Gerard, Matthieu, Bednar, Jan, Arnoult, Christophe, Dimitrov, Stefan, Hamiche, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303386/
https://www.ncbi.nlm.nih.gov/pubmed/35766398
http://dx.doi.org/10.1093/nar/gkac541

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