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Sensitivity to missing not at random dropout in clinical trials: Use and interpretation of the trimmed means estimator

Outcome values in randomized controlled trials (RCTs) may be missing not at random (MNAR), if patients with extreme outcome values are more likely to drop out (eg, due to perceived ineffectiveness of treatment, or adverse effects). In such scenarios, estimates from complete case analysis (CCA) and m...

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Detalles Bibliográficos
Autores principales: Hazewinkel, Audinga‐Dea, Bowden, Jack, Wade, Kaitlin H., Palmer, Tom, Wiles, Nicola J., Tilling, Kate
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303448/
https://www.ncbi.nlm.nih.gov/pubmed/35098576
http://dx.doi.org/10.1002/sim.9299