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Sensitivity to missing not at random dropout in clinical trials: Use and interpretation of the trimmed means estimator
Outcome values in randomized controlled trials (RCTs) may be missing not at random (MNAR), if patients with extreme outcome values are more likely to drop out (eg, due to perceived ineffectiveness of treatment, or adverse effects). In such scenarios, estimates from complete case analysis (CCA) and m...
Autores principales: | Hazewinkel, Audinga‐Dea, Bowden, Jack, Wade, Kaitlin H., Palmer, Tom, Wiles, Nicola J., Tilling, Kate |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303448/ https://www.ncbi.nlm.nih.gov/pubmed/35098576 http://dx.doi.org/10.1002/sim.9299 |
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