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Substrate Profiling of Anion Methyltransferases for Promiscuous Synthesis of S‐Adenosylmethionine Analogs from Haloalkanes

Biocatalytic alkylation reactions can be performed with high chemo‐, regio‐ and stereoselectivity using S‐adenosyl‐l‐methionine (SAM)‐dependent methyltransferases (MTs) and SAM analogs. Currently, however, this methodology is limited in application due to the rather laborious protocols to access SAM...

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Detalles Bibliográficos
Autores principales:	Schülke, Kai H., Ospina, Felipe, Hörnschemeyer, Kathrin, Gergel, Sebastian, Hammer, Stephan C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303522/ https://www.ncbi.nlm.nih.gov/pubmed/34927779 http://dx.doi.org/10.1002/cbic.202100632

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