The T1‐tetramerisation domain of Kv1.2 rescues expression and preserves function of a truncated NaChBac sodium channel

Cytoplasmic domains frequently promote functional assembly of multimeric ion channels. To investigate structural determinants of this process, we generated the ‘T1‐chimera’ construct of the NaChBac sodium channel by truncating its C‐terminal domain and splicing the T1‐tetramerisation domain of the K...

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Detalles Bibliográficos
Autores principales: D’Avanzo, Nazzareno, Miles, Andrew J., Powl, Andrew M., Nichols, Colin G., Wallace, B.A., O’Reilly, Andrias O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303580/
https://www.ncbi.nlm.nih.gov/pubmed/35015304
http://dx.doi.org/10.1002/1873-3468.14279

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303580/
https://www.ncbi.nlm.nih.gov/pubmed/35015304
http://dx.doi.org/10.1002/1873-3468.14279

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