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The T1‐tetramerisation domain of Kv1.2 rescues expression and preserves function of a truncated NaChBac sodium channel
Cytoplasmic domains frequently promote functional assembly of multimeric ion channels. To investigate structural determinants of this process, we generated the ‘T1‐chimera’ construct of the NaChBac sodium channel by truncating its C‐terminal domain and splicing the T1‐tetramerisation domain of the K...
Autores principales: | D’Avanzo, Nazzareno, Miles, Andrew J., Powl, Andrew M., Nichols, Colin G., Wallace, B.A., O’Reilly, Andrias O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303580/ https://www.ncbi.nlm.nih.gov/pubmed/35015304 http://dx.doi.org/10.1002/1873-3468.14279 |
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