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Role of air pollutants mediated oxidative stress in respiratory diseases

Airborne particulate (PM) components from fossil fuel combustion can induce oxidative stress initiated by reactive oxygen species (ROS) that are strongly correlated with airway inflammation and asthma. A valid biomarker of airway inflammation is fractionated exhaled nitric oxide (FENO). The oxidativ...

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Autores principales: Traina, Giovanni, Bolzacchini, Ezio, Bonini, Maira, Contini, Daniele, Mantecca, Paride, Caimmi, Silvia Maria Elena, Licari, Amelia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303668/
https://www.ncbi.nlm.nih.gov/pubmed/35080317
http://dx.doi.org/10.1111/pai.13625
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author Traina, Giovanni
Bolzacchini, Ezio
Bonini, Maira
Contini, Daniele
Mantecca, Paride
Caimmi, Silvia Maria Elena
Licari, Amelia
author_facet Traina, Giovanni
Bolzacchini, Ezio
Bonini, Maira
Contini, Daniele
Mantecca, Paride
Caimmi, Silvia Maria Elena
Licari, Amelia
author_sort Traina, Giovanni
collection PubMed
description Airborne particulate (PM) components from fossil fuel combustion can induce oxidative stress initiated by reactive oxygen species (ROS) that are strongly correlated with airway inflammation and asthma. A valid biomarker of airway inflammation is fractionated exhaled nitric oxide (FENO). The oxidative potential of PM2.5 can be evaluated with the dithiothreitol (DTT) dosage, which represents both ROS chemically produced and intracellular ROS of macrophages. This correlates with quality indicators of the internal environment and ventilation strategies such as dilution and removal of airborne contaminants.
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spelling pubmed-93036682022-07-28 Role of air pollutants mediated oxidative stress in respiratory diseases Traina, Giovanni Bolzacchini, Ezio Bonini, Maira Contini, Daniele Mantecca, Paride Caimmi, Silvia Maria Elena Licari, Amelia Pediatr Allergy Immunol Special Issue: 2021 Update From The Italian Society Of Pediatric Allergy And Immunology Airborne particulate (PM) components from fossil fuel combustion can induce oxidative stress initiated by reactive oxygen species (ROS) that are strongly correlated with airway inflammation and asthma. A valid biomarker of airway inflammation is fractionated exhaled nitric oxide (FENO). The oxidative potential of PM2.5 can be evaluated with the dithiothreitol (DTT) dosage, which represents both ROS chemically produced and intracellular ROS of macrophages. This correlates with quality indicators of the internal environment and ventilation strategies such as dilution and removal of airborne contaminants. John Wiley and Sons Inc. 2022-01-25 2022-01 /pmc/articles/PMC9303668/ /pubmed/35080317 http://dx.doi.org/10.1111/pai.13625 Text en © 2022 The Authors. Pediatric Allergy and Immunology published by European Academy of Allergy and Clinical Immunology and John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Special Issue: 2021 Update From The Italian Society Of Pediatric Allergy And Immunology
Traina, Giovanni
Bolzacchini, Ezio
Bonini, Maira
Contini, Daniele
Mantecca, Paride
Caimmi, Silvia Maria Elena
Licari, Amelia
Role of air pollutants mediated oxidative stress in respiratory diseases
title Role of air pollutants mediated oxidative stress in respiratory diseases
title_full Role of air pollutants mediated oxidative stress in respiratory diseases
title_fullStr Role of air pollutants mediated oxidative stress in respiratory diseases
title_full_unstemmed Role of air pollutants mediated oxidative stress in respiratory diseases
title_short Role of air pollutants mediated oxidative stress in respiratory diseases
title_sort role of air pollutants mediated oxidative stress in respiratory diseases
topic Special Issue: 2021 Update From The Italian Society Of Pediatric Allergy And Immunology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303668/
https://www.ncbi.nlm.nih.gov/pubmed/35080317
http://dx.doi.org/10.1111/pai.13625
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