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Role of air pollutants mediated oxidative stress in respiratory diseases
Airborne particulate (PM) components from fossil fuel combustion can induce oxidative stress initiated by reactive oxygen species (ROS) that are strongly correlated with airway inflammation and asthma. A valid biomarker of airway inflammation is fractionated exhaled nitric oxide (FENO). The oxidativ...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303668/ https://www.ncbi.nlm.nih.gov/pubmed/35080317 http://dx.doi.org/10.1111/pai.13625 |
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author | Traina, Giovanni Bolzacchini, Ezio Bonini, Maira Contini, Daniele Mantecca, Paride Caimmi, Silvia Maria Elena Licari, Amelia |
author_facet | Traina, Giovanni Bolzacchini, Ezio Bonini, Maira Contini, Daniele Mantecca, Paride Caimmi, Silvia Maria Elena Licari, Amelia |
author_sort | Traina, Giovanni |
collection | PubMed |
description | Airborne particulate (PM) components from fossil fuel combustion can induce oxidative stress initiated by reactive oxygen species (ROS) that are strongly correlated with airway inflammation and asthma. A valid biomarker of airway inflammation is fractionated exhaled nitric oxide (FENO). The oxidative potential of PM2.5 can be evaluated with the dithiothreitol (DTT) dosage, which represents both ROS chemically produced and intracellular ROS of macrophages. This correlates with quality indicators of the internal environment and ventilation strategies such as dilution and removal of airborne contaminants. |
format | Online Article Text |
id | pubmed-9303668 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-93036682022-07-28 Role of air pollutants mediated oxidative stress in respiratory diseases Traina, Giovanni Bolzacchini, Ezio Bonini, Maira Contini, Daniele Mantecca, Paride Caimmi, Silvia Maria Elena Licari, Amelia Pediatr Allergy Immunol Special Issue: 2021 Update From The Italian Society Of Pediatric Allergy And Immunology Airborne particulate (PM) components from fossil fuel combustion can induce oxidative stress initiated by reactive oxygen species (ROS) that are strongly correlated with airway inflammation and asthma. A valid biomarker of airway inflammation is fractionated exhaled nitric oxide (FENO). The oxidative potential of PM2.5 can be evaluated with the dithiothreitol (DTT) dosage, which represents both ROS chemically produced and intracellular ROS of macrophages. This correlates with quality indicators of the internal environment and ventilation strategies such as dilution and removal of airborne contaminants. John Wiley and Sons Inc. 2022-01-25 2022-01 /pmc/articles/PMC9303668/ /pubmed/35080317 http://dx.doi.org/10.1111/pai.13625 Text en © 2022 The Authors. Pediatric Allergy and Immunology published by European Academy of Allergy and Clinical Immunology and John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Special Issue: 2021 Update From The Italian Society Of Pediatric Allergy And Immunology Traina, Giovanni Bolzacchini, Ezio Bonini, Maira Contini, Daniele Mantecca, Paride Caimmi, Silvia Maria Elena Licari, Amelia Role of air pollutants mediated oxidative stress in respiratory diseases |
title | Role of air pollutants mediated oxidative stress in respiratory diseases |
title_full | Role of air pollutants mediated oxidative stress in respiratory diseases |
title_fullStr | Role of air pollutants mediated oxidative stress in respiratory diseases |
title_full_unstemmed | Role of air pollutants mediated oxidative stress in respiratory diseases |
title_short | Role of air pollutants mediated oxidative stress in respiratory diseases |
title_sort | role of air pollutants mediated oxidative stress in respiratory diseases |
topic | Special Issue: 2021 Update From The Italian Society Of Pediatric Allergy And Immunology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303668/ https://www.ncbi.nlm.nih.gov/pubmed/35080317 http://dx.doi.org/10.1111/pai.13625 |
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