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Kangaroo mother care had a protective effect on the volume of brain structures in young adults born preterm
AIM: The protective effects of Kangaroo mother care (KMC) on the neurodevelopment of preterm infants are well established, but we do not know whether the benefits persist beyond infancy. Our aim was to determine whether providing KMC in infancy affected brain volumes in young adulthood. METHOD: Stan...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303677/ https://www.ncbi.nlm.nih.gov/pubmed/35067976 http://dx.doi.org/10.1111/apa.16265 |
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author | Charpak, Nathalie Tessier, Rejean Ruiz, Juan Gabriel Uriza, Felipe Hernandez, José Tiberio Cortes, Darwin Montealegre‐Pomar, Adriana |
author_facet | Charpak, Nathalie Tessier, Rejean Ruiz, Juan Gabriel Uriza, Felipe Hernandez, José Tiberio Cortes, Darwin Montealegre‐Pomar, Adriana |
author_sort | Charpak, Nathalie |
collection | PubMed |
description | AIM: The protective effects of Kangaroo mother care (KMC) on the neurodevelopment of preterm infants are well established, but we do not know whether the benefits persist beyond infancy. Our aim was to determine whether providing KMC in infancy affected brain volumes in young adulthood. METHOD: Standardised cognitive, memory and motor skills tests were used to determine the brain volumes of 20‐year‐old adults who had formed part of a randomised controlled trial of KMC versus incubator care. Multivariate analysis of brain volumes was conducted according to KMC exposure. RESULTS: The study comprised 178 adults born preterm: 97 had received KMC and 81 were incubator care controls. Bivariate analysis showed larger volumes of total grey matter, basal nuclei and cerebellum in those who had received KMC, and the white matter was better organised. This means that the volumes of the main brain structures associated with intelligence, attention, memory and coordination were larger in the KMC group. Multivariate lineal regression analysis demonstrated the direct relationship between brain volumes and duration of KMC, after controlling for potential confounders. CONCLUSION: Our findings suggest that the neuroprotective effects of KMC for preterm infants persisted beyond childhood and improved their lifetime functionality and quality of life. |
format | Online Article Text |
id | pubmed-9303677 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-93036772022-07-28 Kangaroo mother care had a protective effect on the volume of brain structures in young adults born preterm Charpak, Nathalie Tessier, Rejean Ruiz, Juan Gabriel Uriza, Felipe Hernandez, José Tiberio Cortes, Darwin Montealegre‐Pomar, Adriana Acta Paediatr Original Articles AIM: The protective effects of Kangaroo mother care (KMC) on the neurodevelopment of preterm infants are well established, but we do not know whether the benefits persist beyond infancy. Our aim was to determine whether providing KMC in infancy affected brain volumes in young adulthood. METHOD: Standardised cognitive, memory and motor skills tests were used to determine the brain volumes of 20‐year‐old adults who had formed part of a randomised controlled trial of KMC versus incubator care. Multivariate analysis of brain volumes was conducted according to KMC exposure. RESULTS: The study comprised 178 adults born preterm: 97 had received KMC and 81 were incubator care controls. Bivariate analysis showed larger volumes of total grey matter, basal nuclei and cerebellum in those who had received KMC, and the white matter was better organised. This means that the volumes of the main brain structures associated with intelligence, attention, memory and coordination were larger in the KMC group. Multivariate lineal regression analysis demonstrated the direct relationship between brain volumes and duration of KMC, after controlling for potential confounders. CONCLUSION: Our findings suggest that the neuroprotective effects of KMC for preterm infants persisted beyond childhood and improved their lifetime functionality and quality of life. John Wiley and Sons Inc. 2022-02-01 2022-05 /pmc/articles/PMC9303677/ /pubmed/35067976 http://dx.doi.org/10.1111/apa.16265 Text en © 2022 The Authors. Acta Paediatrica published by John Wiley & Sons Ltd on behalf of Foundation Acta Paediatrica. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Original Articles Charpak, Nathalie Tessier, Rejean Ruiz, Juan Gabriel Uriza, Felipe Hernandez, José Tiberio Cortes, Darwin Montealegre‐Pomar, Adriana Kangaroo mother care had a protective effect on the volume of brain structures in young adults born preterm |
title | Kangaroo mother care had a protective effect on the volume of brain structures in young adults born preterm |
title_full | Kangaroo mother care had a protective effect on the volume of brain structures in young adults born preterm |
title_fullStr | Kangaroo mother care had a protective effect on the volume of brain structures in young adults born preterm |
title_full_unstemmed | Kangaroo mother care had a protective effect on the volume of brain structures in young adults born preterm |
title_short | Kangaroo mother care had a protective effect on the volume of brain structures in young adults born preterm |
title_sort | kangaroo mother care had a protective effect on the volume of brain structures in young adults born preterm |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303677/ https://www.ncbi.nlm.nih.gov/pubmed/35067976 http://dx.doi.org/10.1111/apa.16265 |
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