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Segregation of the membrane cargoes, BACE1 and amyloid precursor protein (APP) throughout the Golgi apparatus

The intracellular trafficking of β‐site amyloid precursor protein (APP) cleaving enzyme (BACE1) and APP regulates amyloid‐β production. Our previous work demonstrated that newly synthesized BACE1 and APP are segregated into distinct trafficking pathways from the trans‐Golgi network (TGN), and that a...

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Detalles Bibliográficos
Autores principales:	Fourriere, Lou, Cho, Ellie Hyun‐Jung, Gleeson, Paul A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons A/S 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303681/ https://www.ncbi.nlm.nih.gov/pubmed/35076977 http://dx.doi.org/10.1111/tra.12831

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