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Differential Orthopedia Homeobox expression in pulmonary carcinoids is associated with changes in DNA methylation

Limited number of tumor types have been examined for Orthopedia Homeobox (OTP) expression. In pulmonary carcinoids, loss of expression is a strong indicator of poor prognosis. Here, we investigated OTP expression in 37 different tumor types, and the association between OTP expression and DNA methyla...

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Detalles Bibliográficos
Autores principales: Moonen, Laura, Mangiante, Lise, Leunissen, Daphne J. G., Lap, Lisa M. V., Gabriel, Aurelie, Hillen, Lisa M., Roemen, Guido M., Koch, Alexander, van Engeland, Manon, Dingemans, Anne‐Marie C., Foll, Matthieu, Alcala, Nicolas, Fernandez‐Cuesta, Lynnette, Derks, Jules L., Speel, Ernst‐Jan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303689/
https://www.ncbi.nlm.nih.gov/pubmed/35076935
http://dx.doi.org/10.1002/ijc.33939

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