ATF6α promotes prostate cancer progression by enhancing PLA2G4A‐mediated arachidonic acid metabolism and protecting tumor cells against ferroptosis

BACKGROUND: Despite the clinical success of androgen receptor (AR)‐targeted therapies, prostate cancer (PCa) inevitably progresses to castration‐resistant prostate cancer (CRPC). Transcription factor 6 α (ATF6α), an effector of the unfolded protein response (UPR) that modulates the cellular response...

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Detalles Bibliográficos
Autores principales: Zhao, Ru, Lv, Ye, Feng, Tingting, Zhang, Ruojia, Ge, Luna, Pan, Jihong, Han, Bo, Song, Guanhua, Wang, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303695/
https://www.ncbi.nlm.nih.gov/pubmed/35089606
http://dx.doi.org/10.1002/pros.24308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303695/
https://www.ncbi.nlm.nih.gov/pubmed/35089606
http://dx.doi.org/10.1002/pros.24308

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