Large‐scale topological disruption of chromosome territories 9 and 22 is associated with nonresponse to treatment in CML

Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm defined by the presence of t(9;22) translocation whose origin has been associated with the tridimensional genome organization. This rearrangement leads to the fusion of BCR and ABL1 genes giving rise to a chimeric protein with constitut...

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Detalles Bibliográficos
Autores principales: Fabian‐Morales, Eunice, Vallejo‐Escamilla, David, Gudiño, Adriana, Rodríguez, Alfredo, González‐Barrios, Rodrigo, Rodríguez Torres, Yameli L., Castro Hernández, Clementina, de la Torre‐Luján, Alfredo H., Oliva‐Rico, Diego A., Ornelas Guzmán, Erandhi C., López Saavedra, Alejandro, Frias, Sara, Herrera, Luis A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Cancer Genetics and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303775/
https://www.ncbi.nlm.nih.gov/pubmed/34913480
http://dx.doi.org/10.1002/ijc.33903

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