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Generation of a homozygous LRP2 knockout human embryonic stem cell line (FDCHDPe010-A-56) by CRISPR/Cas9 system

LRP2 is mainly expressed in the cell membrane of epithelia, maintaining normal endocytosis of nutrients from the extracellular microenvironment and mediating growth factor signals. The deficiency of LRP2 can result in abnormal lysosomal and mitochondrial function as well as insufficient resistance t...

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Detalles Bibliográficos
Autores principales:	You, Jie, Cheng, Yun, Yang, Xian-Jie, Chen, Ling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303849/ https://www.ncbi.nlm.nih.gov/pubmed/33878707 http://dx.doi.org/10.1016/j.scr.2021.102342

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